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Four months of rifampicin for tuberculosis prevention treatment in children

Published:November 23, 2022DOI:https://doi.org/10.1016/j.jiac.2022.10.016
      We have read with interest the systematic review by Santos et al. in the Journal of Infection and Chemotherapy [
      • Santos J.M.
      • Fachi M.M.
      • Beraldi-Magalhães F.
      • Böger B.
      • Junker A.M.
      • Domingos E.L.
      • et al.
      Systematic review with network meta-analysis on the treatments for latent tuberculosis infection in children and adolescents.
      ]. We congratulate the authors for the choice of their subject. Children exposed to tuberculosis are at high risk for the disease and preventive tuberculosis treatment (TPT) of contact children is a high priority for the United Nations [
      United Nations
      Political Declaration of the UN General Assembly High-Level Meeting.
      ] and the World Health Organization [ ]. However, we are very concerned by the methods and conclusions of their systematic review.
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