Cetobacterium somerae, a gram-negative anaerobic rod, first identified in the feces of children with autism, also colonize freshwater fish intestinal tract. However there have been no reports of human C. somerae infection. Here, we describe the first case of C. somerae bacteremia in a patient with necrotizing cholecystitis. A 72-year-old male presented to the emergency department with chills, vomiting, and fever and was diagnosed with acute necrotizing cholecystitis. An emergency cholecystectomy was performed and the following day, two sets of blood culture were positive for gram-negative bacilli. Identification of C. somerae from the biochemical profile was difficult but possible by mass spectrometry and 16s rRNA sequence.
Abbreviations:AST (antimicrobial susceptibility testing), BLAST (Basic Local Alignment Search Tool), BTB (bromothymol blue), CT (computed tomography), GAM (Gifu anaerobic agar medium), MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry), MIC (minimum inhibitory concentration)
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Published online: May 16, 2023
Accepted: May 2, 2023
Received in revised form: April 14, 2023
Received: February 28, 2023
Publication stageIn Press Corrected Proof
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