Abstract
Cetobacterium somerae, a gram-negative anaerobic rod, first identified in the feces of children with autism,
also colonize freshwater fish intestinal tract. However there have been no reports
of human C. somerae infection. Here, we describe the first case of C. somerae bacteremia in a patient with necrotizing cholecystitis. A 72-year-old male presented
to the emergency department with chills, vomiting, and fever and was diagnosed with
acute necrotizing cholecystitis. An emergency cholecystectomy was performed and the
following day, two sets of blood culture were positive for gram-negative bacilli.
Identification of C. somerae from the biochemical profile was difficult but possible by mass spectrometry and
16s rRNA sequence.
Keywords
Abbreviations:
AST (antimicrobial susceptibility testing), BLAST (Basic Local Alignment Search Tool), BTB (bromothymol blue), CT (computed tomography), GAM (Gifu anaerobic agar medium), MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight mass spectrometry), MIC (minimum inhibitory concentration)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: May 16, 2023
Accepted:
May 2,
2023
Received in revised form:
April 14,
2023
Received:
February 28,
2023
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.